Papers Relating to Challenge Testing
Connell JT. Quantitative intranasal pollen challenges. III The priming effect in allergic rhinitis. J Allergy 1969; 43: 33-44.
Creticos PS, Peters SP, Adkinson NF, Naclerio RM, Hayes EC, Norman PS, Lichtenstein LM. Peptide leukotriene release after antigen challenge in patients sensitive to ragweed. New England Journal of Medicine 1984; 310: 1626-1630.
Day JH and Briscoe M. Environmental exposure unit: a system to test anti-allergic treatment. Ann Allergy Asthma Immunol 1999; 83: 83-93.
Day JH, Briscoe M, Widlitz MD. Cetirizine, loratadine, or placebo in subjects with seasonal allergic rhinitis: effects after controlled ragweed pollen challenge in an environmental exposure unit. J Allergy Clin Immunol 1998; 101: 638-645.
Day JH, Briscoe MP, Rafeiro E, Ellis AK, Pettersson E, Akerlund A. Onset of action of intranasal budesonide (Rhinocort Aqua) in seasonal allergic rhinitis studied in a controlled exposure model. J Allergy Clin Immunol 2000; 105: 489-494.
Donovan JP, Buckeridge DL, Briscoe MP, Clark RH, Day JH. Efficacy of immunotherapy to ragweed antigen tested by controlled antigen exposure. Ann Allergy Asthma Immunol 1996; 77: 74-80.
Gauvreau GM, Lee JM, Watson RM, Irani A-M A, Schwarts LB, O’Byrne PM. Increased numbers of both airway basophils and mast cells in sputum after allergen inhalation challenge of atopic asthmatics. Am J Respir Crit Care Med 2000; 161: 1473-1478.
Hauser R, Rice TM, Murtha GGM, Wand MP, Lewis D, Bledsoe T, Paulauskis J. The upper airway response to pollen is enhanced by exposure to combustion particles: A pilot human experimental challenge study. Environ Health Perspect 2003; 111: 472-477
Simeon DT, Monteil MA. Climatic
variables are associated with seasonal acute asthma admissions to accident and emergency room facilities in
Krug N, Loedding H, Hohlfeld JM, Larbig M, Buckendahl A, Badorrek P, Geldmacher H, Behnke W, Dunkhorst W, Windt H, Luettig B, Koch W. Validation of an environmental exposureunit for controlled human inhalation studies with grass pollen in patients with seasonal allergic rhinitis. Clin Exp Allergy 2003; 33: 1667-1674.
Novey HS, Kozak P,
Piette V, Bousquet C, Kvedariene V, Dhivert-Donnadiew H, Crampette L, Senac J-P, Bousquet J, Demoly P. Sinus CT scans and mediator release in nasal secretions after nasal challenge with cypress pollens. Allergy 2004; 59: 863-868.